Unacylated, acylated ghrelin and obestatin levels are differently inhibited by oral glucose load in pediatric obesity: Association with insulin sensitivity and metabolic alterations

Acylated, unacylated ghrelin and obestatin present different dynamics after glucose load in pediatric individuals. Compensatory insulin secretion to insulin resistance and insulin sensitivity are the major contributors associated with the regulation of ghrelin as well as metabolic alterations with obestatin.