کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2703199 1144581 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Hypoleptinaemia in extreme body mass models: The case of international rugby players
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ارتوپدی، پزشکی ورزشی و توانبخشی
پیش نمایش صفحه اول مقاله
Hypoleptinaemia in extreme body mass models: The case of international rugby players
چکیده انگلیسی

Leptinaemia has been poorly studied in athlete populations with the consequences of athletic hypoleptinaemia yet to be examined. Our aim was to determine if systemic leptinaemia is influenced in high body mass athletes. We recruited 24 rugby players (21.5 ± 4.7 years; 11.8 ± 2.9 h/week) and 26 controls (22.3 ± 3.1 years; 1.9 ± 1.4 h/week). BMD (whole body (WB), limbs, lumbar spine and non-dominant femur) and body composition (WB Lean Mass (LM) and FM) were measured by Dual X-ray Absorptiometry. Circulating levels of serum leptin (ng/ml), adiponectin (μg/ml), insulin (ng/ml), osteocalcin (ng/ml) and CTx (ng/ml) were assessed by ELISA assays. BMD were significantly higher in rugby players vs controls, at all bone sites, yet after adjustments for body mass index. They had significantly higher LM and FM but no differences in %FM. They had significantly higher osteocalcin but lower CTx, insulin and leptin concentrations. Leptin levels were strongly correlated to %FM (r = 0.85, p < 0.0001), as well as to absolute FM (r = 0.77, p = 0.0002), in the rugbymen group. Rugby practice was associated to a bone remodelling process in favour of bone formation. There was a significant hypoleptinaemia in our rugby players, while their percent FM was equivalent and absolute FM significantly higher than the control levels. These data suggest that leptin is under control of physical activity and not just fat mass.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Science and Medicine in Sport - Volume 13, Issue 5, September 2010, Pages 479–484
نویسندگان
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