کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2704899 1144709 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Increased von Willebrand Factor in Acute Stroke Patients With Atrial Fibrillation
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مغز و اعصاب بالینی
پیش نمایش صفحه اول مقاله
Increased von Willebrand Factor in Acute Stroke Patients With Atrial Fibrillation
چکیده انگلیسی
Plasma level of von Willebrand factor (vWF) is a useful marker not only for endothelial dysfunction, but also for left atrial thrombogenesis. We measured plasma levels of vWF antigen and other coagulation and fibrinolysis markers in 183 consecutive patients with acute ischemic stroke and compared these data between patients with and without atrial fibrillation (AF). vWF correlated with severity, outcome, and infarct size and were significantly higher in the AF group than in the non-AF group. The positive correlations of vWF with plasmin-α2 plasmin inhibitor complex and soluble fibrin monomer complex, and higher levels of vWF in patients with than without spontaneous echo contrast, indicate thrombogenesis in the left atrium. Plasma levels of vWF may reflect thrombogenesis in patients with AF.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Stroke and Cerebrovascular Diseases - Volume 15, Issue 1, January–February 2006, Pages 1-7
نویسندگان
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