کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2735802 1147770 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
External beam radiotherapy (EBRT) techniques used in breast cancer treatment to reduce cardiac exposure
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
پیش نمایش صفحه اول مقاله
External beam radiotherapy (EBRT) techniques used in breast cancer treatment to reduce cardiac exposure
چکیده انگلیسی

Radiotherapy in breast cancer treatment has been shown to reduce local recurrence and improve survival rates. However, there is a concern that breast radiotherapy can cause an increase in cardiac mortality, particularly in patients being treated for left-sided breast cancer. This review aims to investigate how cardiac exposure is minimised in breast radiotherapy and determine an optimal method for reducing cardiac dose, using literature from ScienceDirect, Medline and CINAHL. IMRT and breathing-adapted radiotherapy both reduce cardiac exposure but IMRT also increases the irradiated volume at low dose. Several issues were reported with regards to the clinical implementation of these techniques. It is suggested that inspiration breath-hold radiotherapy, is the preferred solution to minimising cardiac exposure but more research is warranted to confirm this. Long-term follow-up is required to determine dose–response relationships. Research needs to focus on breast cancer treatment as a whole in order to effectively reduce cardiac mortality.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Radiography - Volume 19, Issue 1, February 2013, Pages 73–78
نویسندگان
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