کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2735898 | 1147782 | 2011 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Should cerebral microbleeds on magnetic resonance imaging contraindicate thrombolysis in patients with ischaemic stroke?: A systematic review of the evidence Should cerebral microbleeds on magnetic resonance imaging contraindicate thrombolysis in patients with ischaemic stroke?: A systematic review of the evidence](/preview/png/2735898.png)
RationaleCerebral microbleeds (CMBs) may be a marker for increased risk of symptomatic intracranial haemorrhage (SICH) following thrombolysis of patients with ischaemic stroke. This study aims to determine whether the risk of SICH in patients with CMBs is sufficient that thrombolysis should be withheld.MethodologySystematic review, with literature searched using bibliographic databases and cross-referencing from relevant papers to identify papers meeting predefined criteria.ConclusionsCurrent research indicates that while risk of SICH may be slightly elevated in patients with CMBs who receive thrombolysis, it is outweighed by the potential benefits of thrombolysis. It is not clear whether large numbers, or particular patterns, of CMBs indicate significantly increased risk. Evidence was found of inconsistency in both the diagnosis and prevalence of CMBs in the studies. Further research should assess whether severe CMBs indicate a clinically significant risk, and investigate classification and epidemiology of CMBs.
Journal: Radiography - Volume 17, Issue 3, August 2011, Pages 254–259