A Retrospective Study to Evaluate the Work-up and Follow-up of Patients With Monoclonal Gammopathy of Undetermined Significance

BackgroundMonoclonal gammopathy of undetermined significance (MGUS) is a plasma cell proliferative disorder that transforms into multiple myeloma and other serious B-cell disorders at an approximate rate of 1% per year; these patients are also at increased risk for fractures.Patients and MethodsWe conducted a retrospective, multicenter study of 100 patients from seven community health clinics to gain a better understanding of the work-up, follow-up, and treatment of these patients.ResultsMGUS patients appear to undergo inadequate work-up, follow-up, and treatment in the community setting.ConclusionsPhysicians should adhere to recently established guidelines to ensure that MGUS patients receive optimal care for this condition.