کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2758923 1150144 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Impact of an Algorithm on the Optimization of Beta-Blockers After Cardiac Surgery
ترجمه فارسی عنوان
تأثیر یک الگوریتم در بهینه سازی بتا-مسدود کننده ها پس از عمل جراحی قلب
کلمات کلیدی
درمان بتا بلوکر کننده مزمن، جراحی قلب، فیبریلاسیون دهلیزی پس از عمل، بلوک بتا، آریتمی های پس از عمل
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
چکیده انگلیسی

ObjectiveTo evaluate the impact of a simple written algorithm of early postoperative beta-blocker administration on daily practices.DesignA prospective, single center observational study.SettingA 16-bed cardiac surgical intensive care unit in a university teaching hospital.PatientsOne hundred twenty-five consecutive adult patients chronically treated with beta-blockers and scheduled for conventional cardiac surgery.InterventionsTwo successive 4-month phases: Phase 1 = uncontrolled early postoperative beta-blocker administration (n = 73) and phase 2 = beta-blocker administration by an institutional written algorithm using incremental doses of bisoprolol and/or esmolol (n = 52).Measurements and Main ResultsThe main endpoint was the number of patients receiving beta-blockers on the morning of postoperative day 1. Secondary endpoints were the number of patients receiving beta-blockers on the morning of postoperative day 1 and reaching the targeted therapeutic goal and the incidence of postoperative atrial fibrillation in the intensive care unit. A 79% increase in the number of patients receiving beta-blockers on the morning of postoperative day 1 (42% v 75%, p<0.001) was observed during the second phase of the study. The number of patients receiving beta-blockers on the morning of postoperative day 1 and reaching the targeted therapeutic goal was increased significantly by 127% (33% v 75%, p<0.001). The incidence of atrial fibrillation was similar between both phases of the study: 37% versus 31%, p = 0.567.ConclusionsA simple written algorithm markedly improved early postoperative continuation of beta-blockers in chronically treated patients undergoing conventional cardiac surgery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cardiothoracic and Vascular Anesthesia - Volume 29, Issue 1, February 2015, Pages 32–37
نویسندگان
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