کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2759653 1150158 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effectiveness of Laser Doppler Perfusion Monitoring in the Assessment of Microvascular Function in Patients Undergoing On-Pump Coronary Artery Bypass Grafting
ترجمه فارسی عنوان
اثربخشی نظارت بر پالپپرس لیزر در ارزیابی عملکرد مغزی در افراد مبتلا به پیوند عروق کرونر تحت پمپ
کلمات کلیدی
لیزر داپلر، واکنش پذیری میکرو عضلانی پوست، بایپس قلب و ریه نظارت بر پرفیوژن
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
چکیده انگلیسی

ObjectivesTo evaluate the effectiveness of single-point laser Doppler perfusion monitoring (LDPM) in the assessment of microvascular reactivity in the skin during cardiopulmonary bypass (CPB).DesignCross-sectional observational study.SettingGovernment-affiliated teaching hospital.ParticipantsTwenty male patients aged 60±2 years who underwent coronary artery bypass grafting under CPB.InterventionsThe authors assessed the endothelium-dependent vasodilation of the skin microcirculation at the forehead and forearm using LDPM coupled with thermal hyperemia. This measurement was performed before and after the induction of anesthesia, during and after CPB, and 24 h after the end of the surgical procedure.ResultsThe basal values of microvascular flow before the induction of anesthesia were significantly higher in the skin of the forehead compared with that of the forearm. There were no significant alterations in microvascular reactivity throughout the recording periods for both recording sites, as assessed by the vasodilation range expressed as cutaneous vascular conductance (arbitrary perfusion units/mean arterial pressure).ConclusionsUsing LDPM, the authors showed that the microcirculatory bed of the skin of the forehead, which is readily accessible during cardiac surgery, is a suitable model for the study of microvascular reactivity and tissue perfusion in cardiovascular surgical procedures using CPB. This technique could, thus, be suitable for evaluating the effects of drugs or technical procedures on tissue perfusion during cardiac surgery under cardiopulmonary bypass.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cardiothoracic and Vascular Anesthesia - Volume 28, Issue 5, October 2014, Pages 1211–1216
نویسندگان
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