کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2768839 | 1151280 | 2012 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Acidosis láctica asociada a metformina: incidencia, diagnóstico, factores pronóstico y tratamiento
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیهوشی و پزشکی درد
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Acidosis láctica asociada a metformina: incidencia, diagnóstico, factores pronóstico y tratamiento Acidosis láctica asociada a metformina: incidencia, diagnóstico, factores pronóstico y tratamiento](/preview/png/2768839.png)
چکیده انگلیسی
A 76 year-old male patient with diabetes on treatment with metformin, hypertension, dyslipaemia, and with mild cognitive impairment, was admitted to the Intensive Care Unit in a state of circulatory shock, requiring aggressive treatment with vasopressors and volume. The patient had acute kidney injury with an anuria of 3 days, probably secondary to dehydration to vomiting and to NSAIDs. As a result of the acute renal damage, the patient suffered a severe metformin-associated lactic acidosis. The rest of the causes of metabolic acidosis with an increased anion gap were ruled out, as well as a possible sepsis or rhabdomyolysis. Metformin-associated lactic acidosis is an uncommon metabolic condition, but with a high mortality. To reduce the mortality of these patients, it is important to make an early diagnosis using the clinical records, physical examination, and laboratory tests, with an early resuscitation with volume, vasopressors, bicarbonate, and renal replacement therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Española de AnestesiologÃa y Reanimación - Volume 59, Issue 5, May 2012, Pages 276-279
Journal: Revista Española de AnestesiologÃa y Reanimación - Volume 59, Issue 5, May 2012, Pages 276-279
نویسندگان
M. Vives, J. Romano, E. Stoll, A. Lafuente, D. Nagore, P. Monedero,