A novel method of neurostimulation of the peripheral nervous system: The StimRouter implantable device

The nervous system is a dynamic and plastic structure that modulates the transduction and transmission of neuropathic and nociceptive pain. Traditionally, the focus of neuromodulation treatment has been on the central nervous system: spinal cord stimulation, motor cortex stimulation, and deep brain stimulation. Observational experience suggests that peripheral neuromodulatory techniques show promise as peripheral targets, both as stand-alone therapies and as an adjuvant in hybrid systems lead arrays. Currently, there are only a few neuromodulatory devices designed specifically for the periphery. We review one of these novel modalities: the StimRouter. We describe a novel strategy of stimulating named peripheral nerves with the StimRouter. Initial clinical data have shown successful implantation of this novel device and improvement in the acute setting. Currently, a multicenter study is under way to access the success of this novel method of stimulation in the long-term setting. The potential success of the StimRouter could affect peripheral neuromodulatory strategies.