کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2772862 | 1152100 | 2011 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Pheochromocytoma – Current concepts in diagnosis and management Pheochromocytoma – Current concepts in diagnosis and management](/preview/png/2772862.png)
SummaryPheochromocytomas, tumors originating from chromaffin tissue, commonly present with symptoms and signs of catecholamine excess. They may be detected incidentally, as part of multiple endocrine neoplasia, or during unrelated surgery. The previously high mortality (25–40%) has been reduced to <2% primarily due to understanding of catecholamine physiology and adequate preoperative preparation. Advances in molecular biology, genomics, biochemistry and biotechnology often lead to pre-symptomatic diagnosis. Advanced imaging techniques have allowed accurate localization. Availability of an array of vasoactive drugs, monitoring and perioperative care has positively impacted the intra operative course. Finally, advent of laparoscopic and robotic adrenal-sparing adrenalectomy have resulted in reduced hospital stay, earlier oral intake and resumption of normal activity. Management strategies are evolving for the pregnant patient with pheochromocytoma, and the patient with a malignant pheochromocytoma.
Journal: Trends in Anaesthesia and Critical Care - Volume 1, Issue 2, April 2011, Pages 104–110