The T29C polymorphism of the transforming growth factor-β1 (TGF-β1) gene is associated with genetic susceptibility to acute coronary syndrome in Mexican patients

► The TGF-β T29C gene polymorphism was associated with ACS. ► Individuals with TGF-β 29 TT genotype have a 2.5-fold increased risk of developing ACS. ► One risk and one protective haplotype for developing ACS were detected. ► TGF-β1 T29C gene polymorphism could be involved in the risk of developing ACS.