کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2814777 | 1159830 | 2016 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The dynamic changes of DNA methylation in primordial germ cell differentiation
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The dynamic changes of DNA methylation in primordial germ cell differentiation The dynamic changes of DNA methylation in primordial germ cell differentiation](/preview/png/2814777.png)
چکیده انگلیسی
• The latest researches on methylation and demethylation events in the early embryo
• Essential stages for mammalian development
• Hydroxymethylation, significant components of dynamic methylation regulation.
The discovery of DNA methylation has provided a new perspective on how DNA may be dynamically regulated in the mammalian genome. DNA methylation is a dynamic process with a demethylation and de novo methylation from primordial germ cell to differentiation. DNA methylation and demethylation have been proposed to play important roles in somatic cell reprogramming. Some essential components were discussed, such as hydroxymethylation which has recently been confirmed as a modification of developmental importance.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 591, Issue 2, 15 October 2016, Pages 305–312
Journal: Gene - Volume 591, Issue 2, 15 October 2016, Pages 305–312
نویسندگان
Lian Duan, Yongmei Liu, Jie Wang, Jiangquan Liao, Junyuan Hu,