
The dynamic changes of DNA methylation in primordial germ cell differentiation
Keywords: ICM، توده سلولی داخلی; DNMT, DNA methyltransferase; ESCs, embryonic stem cells; PGCs, Primordial germ cells; ICM, inner cell mass; H3K4me3, histone 3 lysine 4 trimethylation; DMRs, Differentially Methylated Regions; Gadd45a, growth arrest and DNA-damage-inducible protein 45 alp