کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2823757 | 1161405 | 2006 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
بوم شناسی، تکامل، رفتار و سامانه شناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population](/preview/png/2823757.png)
چکیده انگلیسی
Polymorphism in SLC11A1 has been implicated in host susceptibility to tuberculosis. We have studied associations between INT4, D543N, and 3′UTR polymorphisms of SLC11A1 and different clinical forms of TB. Analysis used 507 patients with pulmonary TB, 123 with extra pulmonary TB and 513 controls. INT4 and D543N showed allelic association with pulmonary TB (P = 0.02 and 0.03 respectively). INT4–D543N–3′UTR haplotypes showed an association with pulmonary TB (P = 0.03). No association of SLC11A1 with miliary TB was observed, and a possible association of D543N to the pleural form (P = 0.08) was suggested. These results support association between SLC11A1 and TB, particularly to the common pulmonary form.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Infection, Genetics and Evolution - Volume 6, Issue 5, September 2006, Pages 361–367
Journal: Infection, Genetics and Evolution - Volume 6, Issue 5, September 2006, Pages 361–367
نویسندگان
C.A. Taype, J.C. Castro, R.A. Accinelli, P. Herrera-Velit, M.A. Shaw, J.R. Espinoza,