کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2830153 1163359 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Biochemical properties of an intracellular serpin from Echinococcus multilocularis
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی مولکولی
پیش نمایش صفحه اول مقاله
Biochemical properties of an intracellular serpin from Echinococcus multilocularis
چکیده انگلیسی

A serpin of the intracellular type from the tapeworm Echinococcus multilocularis was expressed in Escherichia coli, purified by ion exchange chromatography and tested for inhibitory activity against several proteinases. The recombinant protein, which after transcriptional induction, represents about 20 % of total cellular protein, is biochemically active and inhibits trypsin and the trypsin-like plasmin as well as pig pancreatic and human neutrophil elastase. Implications regarding its biochemistry and biolological function are discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Molecular and Biochemical Parasitology - Volume 156, Issue 1, November 2007, Pages 84–88
نویسندگان
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