کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2833922 | 1164274 | 2013 | 11 صفحه PDF | دانلود رایگان |
Many years of extensive studies of metazoan mitochondrial genomes have established differences in gene arrangements and genetic codes as valuable phylogenetic markers. Understanding the underlying mechanisms of replication, transcription and the role of the control regions which cause e.g. different gene orders is important to assess the phylogenetic signal of such events. This review summarises and discusses, for the Metazoa, the general aspects of mitochondrial transcription and replication with respect to control regions as well as several proposed models of gene rearrangements. As whole genome sequencing projects accumulate, more and more observations about mitochondrial gene transfer to the nucleus are reported. Thus occurrence and phylogenetic aspects concerning nuclear mitochondrial-like sequences (NUMTS) is another aspect of this review.
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► The organisation of mitochondrial genomes is similar but not identical among animals.
► Several different rearrangement operations shape animal mitogenomes.
► Differences in genome structure are reflected in the mito-transcriptome.
Journal: Molecular Phylogenetics and Evolution - Volume 69, Issue 2, November 2013, Pages 328–338