کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2846602 1166435 2006 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
CNS arousal mechanisms bearing on sex and other biologically regulated behaviors
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی فیزیولوژی
پیش نمایش صفحه اول مقاله
CNS arousal mechanisms bearing on sex and other biologically regulated behaviors
چکیده انگلیسی

It now seems possible to move beyond analyzing only the mechanisms for specific sexual behaviors to the analysis of ‘generalized arousal’ that underlies all motivated behaviors. Our science has advanced sufficiently to attack mechanisms linking specific motivations to these general arousal mechanisms that intrinsically activate all biologically-regulated behaviors including ingestive behaviors. Learning from the well-developed reproductive behavior paradigm, we know that sex hormone effects on hypothalamic neurons have been studied to a point where receptor mechanisms are relatively well understood, a neural circuit for a sex steroid-dependent behavior has been worked out, and several functional genomic regulations have been discovered. Here we focus for the first time on three chemical systems that signal ‘generalized arousal’ and which impact hormone-dependent hypothalamic neurons of importance to sexual arousal: histamine, norepinephrine and enkephalin. Progress in linking generalized arousal to specific motivational mechanisms is reviewed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physiology & Behavior - Volume 88, Issue 3, 30 June 2006, Pages 283–293
نویسندگان
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