Design and methodology of the NorthStar study: NT-proBNP stratified follow-up in outpatient heart failure clinics - A randomized Danish multicenter study

This article outlines the design of the NorthStar study. If our hypotheses are confirmed, the results will help cardiologists and nurses in HFCs to identify patients who may benefit from long-term follow-up. Our results may also indicate whether patients with CHF will benefit from adding serial NT-proBNP measurements to usual clinical monitoring.