Comparison of Gender-Specific Mortality in Patients <70 Years Versus ≥70 Years Old With Acute Myocardial Infarction

The aim of the present study was to investigate the gender-specific mortality after acute myocardial infarction in those aged <70 years versus ≥70 years. The present study consisted of 2,677 consecutive patients with acute myocardial infarction who had undergone coronary angiography within 24 hours after the onset of symptoms. The patients were divided into 2 groups: 1,810 patients <70 years old and 867 patients ≥70 years old. Women were older and had a greater incidence of hypertension and diabetes mellitus and a lower incidence of current smoking and previous myocardial infarction in both groups. The in-hospital mortality rate was significantly greater in women ≥70 years old age than in men ≥70 years old (16.2% vs 9.3%, respectively; p = 0.003) but was comparable between women and men in patients <70 years old (5.7% vs 4.9%, respectively; p = 0.59). On multivariate analysis, the association between female gender and in-hospital mortality in patients ≥70 years old remained significant (odds ratio 1.78, 95% confidential interval 1.05 to 3.00), but the gender difference was not observed in patients <70 years old (odds ratio 1.09, 95% confidence interval 0.53 to 2.24). In conclusion, female gender was associated with in-hospital mortality after acute myocardial infarction in patients ≥70 years old but not in patients <70 years old.