کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2861154 1572382 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Analysis of Interaction of Acute Atrial Overdrive Pacing with Sleep-Related Breathing Disorder†
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Analysis of Interaction of Acute Atrial Overdrive Pacing with Sleep-Related Breathing Disorder†
چکیده انگلیسی

Dose-related effects of atrial overdrive pacing (AOP) on sleep-related breathing disorder (SRBD) were studied. Fourteen patients with pacemakers with moderate to severe SRBD (mean screening apnea-hypopnea index [AHI] 35.2 ± 21.9 events/hour) were randomized to 3 levels of pacing (50, 10, and 20 beats/min greater than the mean nocturnal heart rate) and studied by polysomnography, observing for changes in AHI. At the 2 AOP levels, no significant change was observed in the primary end point of reduction in AHI. Additionally, there was no observed impact on secondary end points of the study. Cyclic variation of heart rate was progressively abolished with higher levels of AOP without affecting AHI. Large variations were observed between the screening and control studies in SRBD indexes in a number of patients. In conclusion, AOP demonstrated no benefit to predominantly obstructive SRBD disorder of at least moderate severity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Cardiology - Volume 99, Issue 4, 15 February 2007, Pages 573–578
نویسندگان
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