Decreased Interleukin 35 and CD4+EBI3+T cells in Patients With Active Systemic Lupus Erythematosus

These results demonstrate that abnormalities in IL-35 and CD4+EBI3+ T cells may play important roles in the pathogenesis of SLE; the percentage of double-positive T cells and the level of IL-35 are parameters for the evaluation of SLE activity and severity.