Heart Failure With Preserved Left Ventricular Function: Diagnostic and Therapeutic Challenges in Patients With Diastolic Heart Failure

Heart failure associated with preserved left ventricular ejection fraction (HFpEF) is a condition of increasing importance, not only due to its rising prevalence but also due to the lack of clinical evidence for pharmacologic therapies that are beneficial. Thus, a recent case encountered at the Vanderbilt University Medical Center illustrates the clinical challenges one may encounter in patients with HFpEF. A careful review of the diagnostic challenges of HFpEF or diastolic heart failure, current recommendations for management and a glimpse of upcoming research are presented.