Outcomes of Tacrolimus Therapy in Adults With Refractory Membranous Nephrotic Syndrome: A Prospective, Multicenter Clinical Trial

TAC plus prednisone may be an alternative therapeutic option for steroid and general immunosuppressant-resistant membranous nephrotic syndrome patients, with a favorable safety profile. However, given the limitation of a small number of patients in this trial, further study with a larger number and longer follow-up is needed.