Routine Pneumococcal Vaccination of Children Provokes New Patterns of Serotypes Causing Invasive Pneumococcal Disease in Adults and Children

Routine PCV7 decreased IPD in children but not in adults. Predominant STs changed-children exhibited fewer PCV7 STs and adults exhibited fewer PCV7 and PPV23 STs-reducing vaccine coverage and increasing the risk of replacement STs causing IPD in adults.