کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2865042 | 1573222 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Positron Emission Tomography-Positive Squalene-induced Lipoid Pneumonia Confirmed by Gas Chromatography-Mass Spectrometry of Bronchoalveolar Lavage Fluid
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Positron Emission Tomography-Positive Squalene-induced Lipoid Pneumonia Confirmed by Gas Chromatography-Mass Spectrometry of Bronchoalveolar Lavage Fluid Positron Emission Tomography-Positive Squalene-induced Lipoid Pneumonia Confirmed by Gas Chromatography-Mass Spectrometry of Bronchoalveolar Lavage Fluid](/preview/png/2865042.png)
چکیده انگلیسی
Squalene is a type of oil obtained from shark liver. We describe a 76-year-old man diagnosed with chronic exogenous lipoid pneumonia due to squalene. A chest CT scan revealed pulmonary consolidation with ground-glass opacities in the right upper lobe. Positron emission tomography (PET) revealed significant uptake of 2-deoxy-2-18F-fluoro-d-glucose (FDG) and 3â²-deoxy-3â²-18F-fluorothymidine (FLT). Bronchoalveolar lavage (BAL) fluid contained many lipid-laden macrophages, and a transbronchial lung biopsy specimen showed clusters of foamy macrophages in alveolar spaces and granulomatous lesions. In addition, the presence of squalene in the BAL fluid was confirmed by gas chromatography-mass spectrometry, leading to a diagnosis of squalene-induced lipoid pneumonia. To the best of our knowledge, this is the first report of squalene-induced lipoid pneumonia in which squalene itself was successfully detected. This case also suggests the possibility that lipoid pneumonia shows significant uptake in FDG-PET and FLT-PET.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of the Medical Sciences - Volume 335, Issue 4, April 2008, Pages 310-314
Journal: The American Journal of the Medical Sciences - Volume 335, Issue 4, April 2008, Pages 310-314
نویسندگان
Nobuhiro MD, Shuji MD, Koshiro MD, Toshihiko MD, Kyuichi MD, Reiji MD, Toru CT, IAC, Kohoji CT, IAC, Yoshio MD, Yuka MD,