Ten years cardiovascular risk estimation according to Framingham score and non HDL-cholesterol in blood donors

Cardiovascular disease (CVD) is currently the primary cause of morbidity and mortality.Aims(1) Assess the 10 years risk for CVD in Argentinean blood donors, according to Framingham score (updated by ATP III), (2) evaluate the prevalence of the MS, (3) evaluate non HDL-cholesterol level in this population as other risk for CVD.Materials and methodsA prospective, epidemiological, transversal study was performed to evaluate 585 volunteer blood donors for two years. Non HDL-C was calculated as total cholesterol minus HDL-C and we evaluated the 10 years risk for CVD according to Framingham score (updated by ATP III).ResultsMetabolic syndrome prevalence was estimated according to ATP III and IDF criteria. Non HDL-C was (media ± SD) 178.3 ± 48.0 mg/dl in participants with MS and 143.7 ± 39.3 mg/dl without MS (ATPIII) and 160.1 ± 43.6 mg/dl in participants with MS and 139.8 ± 43.1 mg/dl without MS (IDF). Participants with MS presented an OR of 3.1; IC 95% (2–5) of CVD according to de Framingham score.ConclusionIndividuals with MS and elevated non HDL-C are at a higher estimated risk for cardiovascular events in the next 10 years according to the Framingham risk score.