کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2912970 1575478 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Postural and Ambulatory Changes in Regional Flow and Skin Perfusion
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Postural and Ambulatory Changes in Regional Flow and Skin Perfusion
چکیده انگلیسی

BackgroundStudies of orthostatic changes in cutaneous micro-perfusion have yielded conflicting results, likely from imprecision of legacy equipment.MethodsPostural flow changes in the femoral vessels and cervical carotids were measured in healthy normal adults using duplex equipment. Nutrient skin flow was measured using Hyperspectral imager (OxyVu-2™), a newer non-touch measurement technology.ResultsThere are regional variations in cutaneous capillary density, sparse in the abdomen but richer in the forehead and ankle. Orthostatic microvascular congestion displays regional variations reflective of the non-linear pressure–volume relationship in thin walled vessels. There is profound cutaneous deoxygenation (≈40% reduction) in the lower body starting at the level of the umbilicus and involving all levels below, in the erect posture; upper body is unaffected. Quantitative regional flow is preserved however, with an increase in pulse rate despite a velocity decrease in the femoral vessels. Increasing the arterio-venous gradient by calf-emptying maneuvers resulted in little improvement in cutaneous oxygenation unable to overcome the powerful orthostatic vasoconstriction.ConclusionThere is intense orthostatic vasoconstriction and cutaneous deoxygenation of the lower limbs to a degree not previously suspected. This powerful mechanism may be relevant to an understanding of dysvascular syndromes, particularly those with strong orthostatic features.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Vascular and Endovascular Surgery - Volume 43, Issue 5, May 2012, Pages 567–572
نویسندگان
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