کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2913907 | 1575483 | 2011 | 12 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: A Meta-analysis and Metaregression Analysis of Factors Influencing Mortality after Endovascular Repair of Ruptured Abdominal Aortic Aneurysms A Meta-analysis and Metaregression Analysis of Factors Influencing Mortality after Endovascular Repair of Ruptured Abdominal Aortic Aneurysms](/preview/png/2913907.png)
ObjectiveTo determine factors that may influence the perioperative mortality after endovascular repair of ruptured abdominal aortic aneurysms (RAAAs) using metaregression analysis.MethodsA meta-analysis of all English-language literature with information on mortality rates after endovascular repair of RAAAs was conducted. A metaregression was subsequently performed to determine the impact on mortality of the following 8 factors: patient age; mid-time study point; anaesthesia; endograft configuration; haemodynamic instability; use of aortic balloon; conversion to open repair; and abdominal compartment syndrome.ResultsThe pooled perioperative mortality across the 46 studies (1397 patients) was 24.3% (95% CI: 20.7–28.3%). Of the 8 variables, only bifurcated approach was significantly associated with reduced mortality (p = 0.005). A moderate negative correlation was observed between bifurcated approach and haemodynamic instability (−0.35). There was still a strong association between bifurcated approach and mortality after simultaneously adjusting for haemodynamic instability, indicating that the latter was not a major factor in explaining the observed association.ConclusionsEndovascular repair of RAAAs is associated with acceptable mortality rates. Patients having a bifurcated endograft were less likely to die. This may be due to some surgeons opting for a bifurcated approach in patients with better haemodynamic condition. Further studies will be needed to clarify this.
Journal: European Journal of Vascular and Endovascular Surgery - Volume 42, Issue 6, December 2011, Pages 775–786