کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2930028 1576251 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
HbA1c and atrial fibrillation: A cross-sectional study in Japan
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
HbA1c and atrial fibrillation: A cross-sectional study in Japan
چکیده انگلیسی

BackgroundThe aim of the present study was to investigate whether the prevalence of atrial fibrillation (AF) is associated with the level of glycated hemoglobin (HbA1c) in Japanese adults in Kurashiki-city.MethodsAdult residents (≧ 40 years old) were examined twice, in 2006 and 2007. Electrocardiography was conducted to determine the presence of AF. After categorizing all participants into two groups (HbA1c < 6.5% as low group and ≧ 6.5% as high group), factors independently associated with the prevalence of AF were investigated in total cohort, low and high groups using multivariate logistic regression analysis.ResultsOf the total 52,448 participants (median age, 72 years; range, 65–78 years; 17,980 men), AF prevalence was 2.2% (1161/52,448). After classifying all participants by HbA1c level, the proportion of participants with AF was 2.2% (1073/49,498) in the low group and 3.0% (88/2950) in high group (p = 0.005). AF was significantly associated with cardiac disease (OR, 5.78; 95%CI, 5.07–6.58; p < 0.001), elevating HbA1c (OR, 1.57; 95%CI, 1.33–1.84; p < 0.001), increasing age (OR, 1.40; 95%CI, 1.30–1.51; p < 0.001), and male sex (OR, 1.27; 95%CI, 1.10–1.47; p = 0.001) in low group and was related to cardiac disease (OR, 4.85; 95%CI, 3.08–7.62; p < 0.001) and age (OR, 1.45; 95%CI, 1.09–1.93; p = 0.010) in high group. After adjusted age, gender, vascular risk factors, cardiac disease, and eGFR, elevating HbA1c (OR, 1.18; 95%CI, 1.09–1.28; p < 0.001) was the factor in association with AF.ConclusionsThe presence of AF appears to be associated with the level of HbA1c, especially in patients with HbA1c < 6.5%.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Cardiology - Volume 156, Issue 2, 19 April 2012, Pages 156–159
نویسندگان
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