کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2941524 | 1177074 | 2010 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Septal Pouch in the Left Atrium : A New Anatomical Entity With Potential for Embolic Complications Septal Pouch in the Left Atrium : A New Anatomical Entity With Potential for Embolic Complications](/preview/png/2941524.png)
ObjectivesThe purpose of this study was to develop a better understanding of the pathophysiology of the condition, we studied the patterns by which the septum primum (SP) and septum secundum (SS) fuse.BackgroundA patent foramen ovale (PFO) is a communication across the interatrial septum between a nonadherent SP and SS and is considered to be a risk factor for serious clinical syndromes.MethodsWe examined the interatrial septum in 94 randomly selected autopsied hearts, with a focus on the SP and SS and the patterns by which the 2 structures fuse.ResultsOf the 94 specimens that were suitable for analysis, 26 (27.66%) had a PFO. Of the remaining 68 hearts, complete fusion of the SP and SS along the entire zone of overlap was seen in 27 (28.7%) hearts. In the remaining 41 hearts (60.29%), a PFO was absent, but incomplete fusion of the SP and SS was seen. Of 41 hearts, 37 (90%) had a septal pouch that opened into the left atrial (LA) cavity. Four hearts (10%) had a pouch accessible from the right atrium. Hearts with left-sided pouches tended to be younger (50 ± 18 years of age) than hearts where there was complete fusion (age 63 ± 23 years) (p = 0.06).ConclusionsOur data suggest that when a foramen ovale closes spontaneously, the SP and SS fuse initially at the caudal limit of the zone of overlap of the 2 structures. This incomplete fusion results in a pouch that, in the majority of instances, communicates with the LA cavity.
Journal: JACC: Cardiovascular Interventions - Volume 3, Issue 1, January 2010, Pages 98–104