کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2953026 1577416 2008 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Central But Not Brachial Blood Pressure Predicts Cardiovascular Events in an Unselected Geriatric Population: The ICARe Dicomano Study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Central But Not Brachial Blood Pressure Predicts Cardiovascular Events in an Unselected Geriatric Population: The ICARe Dicomano Study
چکیده انگلیسی

ObjectivesThe present study investigated whether central blood pressure (BP) predicts cardiovascular (CV) events better than brachial BP in a cohort of normotensive and untreated hypertensive elderly individuals.BackgroundLimited and conflicting data have been reported on the prognostic relevance of central BP compared with brachial BP.MethodsCommunity-dwelling individuals ≥65 years of age, living in Dicomano, Italy, underwent an extensive clinical assessment in 1995 including echocardiography and carotid ultrasonography and applanation tonometry. In 2003, vital status and CV events were assessed, reviewing the electronic database of the Regional Ministry of Health. Only normotensive (n = 173) and untreated hypertensive subjects (95 diastolic and 130 isolated systolic) were included in the present analysis.ResultsDuring 8 years, 106 deaths, 45 of which were cardiovascular, and 122 CV events occurred. In univariate analyses, both central and brachial systolic blood pressure (SBP) and pulse pressure (PP) predicted CV events (all p < 0.005); however, in multivariate analyses, adjusting for age and gender, higher carotid SBP and PP (hazard ratios 1.19/10 and 1.23/10 mm Hg, respectively; both p < 0.0001) but neither brachial SBP nor PP independently predicted CV events. Similarly, higher carotid SBP but not brachial pressures independently predicted CV mortality (hazard ratio 1.37/10 mm Hg; p < 0.0001).ConclusionsOur prospective study in an unselected geriatric population demonstrates superior prognostic utility of central compared with brachial BP.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American College of Cardiology - Volume 51, Issue 25, 24 June 2008, Pages 2432–2439
نویسندگان
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