کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2962686 1405948 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Myocardial dysfunction identified by three-dimensional speckle tracking echocardiography in type 2 diabetes patients relates to complications of microangiopathy
ترجمه فارسی عنوان
اختلال قند خون ناشی از اکوکاردیوگرافی ردیابی سهبعدی در بیماران دیابتی نوع 2 مربوط به عوارض میکروآنژیوپاتی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی

BackgroundThe clinical effect of diabetic microangiopathy on left ventricular (LV) function is still uncertain. The purpose of this study was to assess the relation between diabetic microvascular complications and comprehensive myocardial deformation measurements using three-dimensional (3D) speckle tracking echocardiography.MethodsSeventy-seven asymptomatic patients with type 2 diabetes mellitus (DM) and 35 age-matched healthy control subjects underwent 3D echocardiography. Patients with coronary artery disease or LV ejection fraction <50% were excluded. Presence of proliferative retinopathy, microalbuminuria as nephropathy, and decreased coefficient of variation of R-R intervals (CVRR) <3% as cardiac autonomic neuropathy were defined as diabetic microvascular complications.ResultsLV ejection fraction, LV mass index, and global radial strain did not differ between control and DM patients. However, global longitudinal and circumferential strain and endocardial area change ratio were lower in patients with DM than in the controls (−12.0 ± 3.0% vs. −16.2 ± 1.9%, −27.7 ± 7.1% vs. 32.2 ± 5.7%, −37.6 ± 7.6% vs. 44.0 ± 6.2%, respectively, p < 0.001). In DM patients, longitudinal strain is related to CVRR (R = 0.58, p < 0.001), retinopathy stage, and nephropathy stage.ConclusionsDiabetic microangiopathy and its accumulated effects significantly related to subclinical LV dysfunction are characterized by impaired longitudinal shortening.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cardiology - Volume 68, Issue 4, October 2016, Pages 282–287
نویسندگان
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