کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2969276 1178902 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Distinctive impaired cardiac autonomic modulation of heart rate variability in chronic Chagas' indeterminate and heart diseases
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Distinctive impaired cardiac autonomic modulation of heart rate variability in chronic Chagas' indeterminate and heart diseases
چکیده انگلیسی

IntroductionCardiac autonomic dysfunction occurs in Chagas' indeterminate and heart disease, but comparison of this disturbance between both forms was not yet performed.MethodsTime- and frequency-domain 5-minute heart rate variability in supine and standing positions were evaluated in 17 subjects with Chagas' disease with the indeterminate form, 13 with heart disease and 15 controls. Trend of variability indices across the groups was also tested.ResultsIn the supine position, reduced time-domain and absolute frequency-domain indices reflecting overall autonomic modulation were observed in both Chagas' disease groups. In the standing position, the coefficient of variation and those frequency-domain indices were also reduced, and the other time-domain indices were reduced only in the cardiac group. Heart rate variability indices hypothesized to reflect relative sympathetic and parasympathetic activity showed no alteration. A significant graded reduction was observed in the altered indices in both postures, from the control to the Chagas' indeterminate and heart disease groups.ConclusionCardiac autonomic dysfunction, with preserved putative measures of sympathetic and parasympathetic modulation in relative terms, was less severe or absent in the indeterminate and pronounced in cardiac form of Chagas' disease.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Electrocardiology - Volume 42, Issue 3, May–June 2009, Pages 281–289
نویسندگان
, ,