کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2970982 1578277 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reduction of alloantibodies via proteosome inhibition in cardiac transplantation
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Reduction of alloantibodies via proteosome inhibition in cardiac transplantation
چکیده انگلیسی
In this pilot study, use of plasmapheresis and bortezomib appeared to decrease cPRA, even in patients refractory to desensitization with IVIg/rituximab, thus increasing the chances that an acceptable donor heart will be available for the sensitized patient awaiting heart transplantation. However, desensitization is associated with an increased risk of infection. Further studies are warranted to determine whether the benefits of desensitization using this strategy outweigh the risks.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Heart and Lung Transplantation - Volume 30, Issue 12, December 2011, Pages 1320-1326
نویسندگان
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