کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3003860 1180823 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Adipocyte response to conjugated linoleic acid
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Adipocyte response to conjugated linoleic acid
چکیده انگلیسی

SummaryConjugated linoleic acid (CLA), which is a generic term to describe isomers of octadecadienoic acid, has been reported to exert various beneficial physiological effects. Accumulating data show that CLA, especially trans10, cis12 (t10, c12)-CLA, has a potent body fat-reducing effect, which is prominent in mice and to a lesser extent rats. In addition, several clinical studies have demonstrated the body fat- and weight-reducing effect of CLA in humans. However, t10, c12-CLA evokes severe lipodystrophy in mice that results in impaired glucose metabolism. Therefore, while CLA is a promising agent for the amelioration of obesity and obesity-related diseases, it is important to establish its safety prior to common use in humans. In addition, it is important to elucidate the details of the molecular mechanisms of CLA. Here, we focus on the response of adipocyte to CLA.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Obesity Research & Clinical Practice - Volume 7, Issue 4, July–August 2013, Pages e235–e242
نویسندگان
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