Outcomes following heart transplantation in children

Despite discouraging late survival estimates based on historical experience, improving survival in more recent eras will probably result in improved long term survival in future years. Development of new strategies for immunosuppression, particularly those aimed at reducing graft loss from chronic rejection, may also significantly improve long term survival. In addition, tailoring therapy to those who are at high risk, including those with high risk due to elevated PRA and those with other risk factors may improve long term survival.