کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3014601 | 1181900 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Mixomas cardiacos y complejo de Carney
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
The study involved 63 patients with an echocardiographic, surgical and histopathologic diagnosis of cardiac myxoma who were seen over a period of 20 years. Tumor recurrence or relapse was documented in five of these patients (7.9%), 3 of whom had a confirmed diagnosis of Carney complex, while one other patient had a probable diagnosis. Genetic studies demonstrated abnormalities in the PRKAR1A gene on chromosome 17 in 2 patients and their immediate family. In 11 of the 58 patients who did not experience relapse of the myxoma, genetic studies failed to show any abnormality. In conclusion, the possible presence of the Carney complex should be investigated in patients with multiple myxomas or with a cardiac myxoma whose location is atypical.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Española de CardiologÃa - Volume 61, Issue 11, November 2008, Pages 1205-1209
Journal: Revista Española de CardiologÃa - Volume 61, Issue 11, November 2008, Pages 1205-1209
نویسندگان
Jesus Vargas-Barrón, Gilberto Vargas-Alarcón, Francisco-Javier Roldán, Clara Vázquez-Antona, Zuilma Vásquez Ortiz, Julio Erdmenger-Orellana, Angel Romero-Cárdenas,