Prevalence of Chronic Kidney Disease in Patients With or at a High Risk of Cardiovascular Disease

This secondary analysis of data from the MULTIRISC study investigated the prevalence of chronic kidney disease (CKD) in patients who either had or were at a high risk of cardiovascular disease. The original, epidemiological, cross-sectional, multicenter study was carried out in outpatient clinics belonging to cardiology, internal medicine and endocrinology departments. It included patients aged ≥18 years with a high cardiovascular risk (ie, a SCORE [Systematic Coronary Risk Evaluation] risk >5% or diabetes mellitus or associated clinical disease). The definition of CKD was an estimated glomerular filtration rate (Modification of Diet in Renal Disease formula) <60 mL/min per 1.73 m2. Established CKD was regarded as present when, in addition, the serum creatinine level was ≥1.3 mg/dL in men or ≥1.2 mg/dL in women, and occult CKD as present when the creatinine level was lower. In total, 2608 patients were included. Some 62.7% did not have CKD, 18.9% had established CKD, and 18.4% had occult CKD. In summary, CKD was highly prevalent in patients with a high risk of cardiovascular disease.

Este subanálisis del estudio MULTIRISC evaluó la prevalencia de insuficiencia renal crónica (IRC) en pacientes con alto riesgo o enfermedad cardiovascular. Se trata de un estudio epidemiológico, transversal y multicéntrico realizado en consultas externas de cardiología, medicina interna o endocrinología. Se incluyó a pacientes con 18 años o más, con alto riesgo cardiovascular (SCORE > 5% o diabetes o enfermedad clínica concomitante). Se definió IRC si el filtrado glomerular estimado (MDRD) era < 60 ml/ min/1,73 m2; IRC establecida si además la creatinina era ≥ 1,3 mg/dl en varones o ≥ 1,2 mg/dl en mujeres, e IRC oculta cuando la creatinina era inferior. Se incluyó a 2.608 pacientes. El 62,7% no presentaba IRC, el 18,9% presentaba IRC establecida y el 18,4%, IRC oculta. La IRC es muy prevalente en pacientes con alto riesgo cardiovascular.