Effect of Age on Valvular Dysfunction and Aortic Dilatation in Patients With a Bicuspid Aortic Valve

Aortic regurgitation was the commonest functional anomaly among younger patients in a group of 63 individuals with a diagnosis of bicuspid aortic valve. With increasing age, a rise in the number with combined aortic valve disease and aortic stenosis was observed. Aortic dilatation was found in 65% of cases. Dilatation was independently associated with age and transvalvular aortic gradient.