Seguridad a largo plazo de los stents recubiertos. El fenómeno de la trombosis tardía

The introduction of drug-eluting stents is regarded as one of the landmarks of percutaneous coronary intervention for ischemic heart disease. In a very short time, they were universally accepted throughout the world and the number of units implanted grew exponentially. After several years of excessive enthusiasm, during which these stents demonstrated, without doubt, clear benefits for the Achilles' heel of coronary angioplasty, namely the problem of restenosis, a number of doubts about the long-term safety of these devices began to arise. These stemmed from the appearance of cases of late intrastent thrombosis, sometimes occurring in a much later time period, which had adverse consequences for patients.