کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3027513 1182976 2012 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Blood platelet biochemistry
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Blood platelet biochemistry
چکیده انگلیسی

Defects in platelet function or formation increase the risk for bleeding or thrombosis, which indicates the crucial role for platelets in maintaining haemostasis in normal life. Upon vascular injury, platelets instantly adhere to the exposed extracellular matrix which results in platelet activation and aggregation and the formation a haemostatic plug that stops bleeding. To prevent excessive platelet aggregate formation that eventually would occlude the vessels, this self-amplifying process nevertheless requires a tight control. This review intends to give a comprehensive overview of the currently established main mechanisms in platelet function.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Thrombosis Research - Volume 129, Issue 3, March 2012, Pages 245–249
نویسندگان
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