کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3027972 1182996 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Membrane microparticles in VTE and cancer
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Membrane microparticles in VTE and cancer
چکیده انگلیسی

Microparticles (MPs) are cellular vesicles produced by all cells in response to apoptosis or cellular activation. In this brief review, the evidence that MPs mediate the thrombotic propensity that characterizes patients with cancer is evaluated. It is concluded that while considerable data exist to support a critical pathophysiologic role of host or tumor cell-derived MPs in cancer-associated thrombosis, causality is not yet firmly established. The results of prospective clinical studies that are currently underway should clarify any causative relationship.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Thrombosis Research - Volume 125, Supplement 2, April 2010, Pages S80-S83