کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3031990 | 1183991 | 2015 | 11 صفحه PDF | دانلود رایگان |
IntroductionSubjective cognitive decline (SCD) may indicate unhealthy cognitive changes, but no standardized SCD measurement exists. This pilot study aimed to identify reliable SCD questions.MethodsA total of 112 cognitively normal (NC; 76 ± 8 years; 63% female), 43 mild cognitive impairment (MCI; 77 ± 7 years; 51% female), and 33 diagnostically ambiguous participants (79 ± 9 years; 58% female) were recruited from a research registry and completed 57 self-report SCD questions. Psychometric methods were used for item reduction.ResultsFactor analytic models assessed unidimensionality of the latent trait (SCD); 19 items were removed with extreme response distribution or trait-fit. Item response theory (IRT) provided information about question utility; 17 items with low information were dropped. Post hoc simulation using computerized adaptive test (CAT) modeling selected the most commonly used items (n = 9 of 21 items) that represented the latent trait well (r = 0.94) and differentiated NC from MCI participants (F [1, 146] = 8.9, P = .003).DiscussionIRT and CAT modeling identified nine reliable SCD items. This pilot study is a first step toward refining SCD assessment in older adults. Replication of these findings and validation with Alzheimer's disease biomarkers will be an important next step for the creation of a SCD screener.
Journal: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring - Volume 1, Issue 4, December 2015, Pages 429–439