کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3035577 1184273 2007 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Autonomic nervous system and secretion across the intestinal mucosal surface
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب سلولی و مولکولی
پیش نمایش صفحه اول مقاله
Autonomic nervous system and secretion across the intestinal mucosal surface
چکیده انگلیسی

Chloride secretion is important because it is the driving force for fluid movement into the intestinal lumen. The flow of accumulated fluid flushes out invading micro-organisms in defense of the host. Chloride secretion is regulated by neurons in the submucosal plexus of the enteric nervous system. Mechanosensitive enterochromaffin cells that release 5-hydroxytryptamine (5-HT) and activate intrinsic afferent neurons in the submucosal plexus and initiate chloride secretion. Mechanical stimulation by distention may also trigger reflexes by a direct action on intrinsic afferent neurons. Dysregulation of 5-HT release or altered activity of intrinsic afferents is likely to occur in states of inflammation and other disorders.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autonomic Neuroscience - Volume 133, Issue 1, 30 April 2007, Pages 55–63
نویسندگان
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