کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3036600 1184377 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cerebellar injury in preterm children with cerebral palsy after intraventricular hemorrhage: Prevalence and relationship to functional outcomes
ترجمه فارسی عنوان
آسیب مغزی در کودکان مبتلا به فلج مغزی پس از خونریزی داخل وریدی: شیوع و ارتباط با نتایج عملکردی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب تکاملی
چکیده انگلیسی

ObjectivesTo elucidate the prevalence of cerebellar injury and its relationship to functional outcomes in preterm children with cerebral palsy (CP) after intraventricular hemorrhage (IVH).ParticipantsWe selected 69 children (40 males and 29 females, aged between 6 and 13 years) out of 2049 with cerebral palsy who visited Morinomiya Hospital, the regional center hospital for CP in West Japan. The inclusion criteria were (1) gestational age under 36 weeks at birth, (2) clear history of postnatal intraventricular hemorrhage, and (3) age at investigation over 6 years old. Those without sufficient imaging study or functional evaluation were excluded.MethodsThe participants were divided into four groups according to the presence of post-hemorrhagic hydrocephalus (PH) and cerebellar injury (CI): PH+/CI+, PH+/CI−, PH−/CI+, and PH−/CI−. Type of CP, ability to walk, verbal function, the incidence of severe visual impairment, and the complication of epilepsy were investigated and compared among the groups.ResultsThe gestational ages of the participants were between 22 and 34 weeks, and their birth weight was between 412 and 1788 g. PH and CI were found in 39 (57%) and 40 (58%) children, respectively. Both the PH+/CI+ group (n = 31) and the PH−/CI+ group (n = 9) showed significantly lower walking and verbal abilities and a higher incidence of epilepsy than the PH−/CI− group (n = 21), while the PH+/CI− group showed no significant difference from the PH−/CI− group. Severe visual impairment was found only in the PH+/CI+ group and the PH−/CI+ group.ConclusionsThe prevalence of CI in preterm children with CP after IVH (58%) was almost the same as that of PH. CI is one of the most significant complications in preterm infants, affecting motor and verbal functions and being associated with epilepsy more than PH.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain and Development - Volume 37, Issue 8, September 2015, Pages 758–763
نویسندگان
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