کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3038519 1184470 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fluctuating hearing loss, episodic headache, and stroke with platelet hyperaggregability: Coexistence of auditory neuropathy and cochlear hearing loss
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب تکاملی
پیش نمایش صفحه اول مقاله
Fluctuating hearing loss, episodic headache, and stroke with platelet hyperaggregability: Coexistence of auditory neuropathy and cochlear hearing loss
چکیده انگلیسی

We encountered a 10-year-old girl with fluctuating sensorineural hearing loss, episodic headache, and white matter stroke. Strenuous exercise, febrile illness, and general anesthesia all temporarily worsened hearing. Audiologic findings were asymmetric: left-sided retrocochlear dysfunction consistent with auditory neuropathy contrasted with cochlear hearing loss in the right ear. Platelets obtained during a headache-free period showed excessive responsiveness to collagen in vitro, while episodic elevations of thromboxane B2 and thrombin–antithrombin III complex were noted in blood sampled during headache. Treatment of hyperaggregability of platelets with aspirin and antioxidant vitamins relieved headache, while adenosine triphosphate administration improved hearing thresholds. In this patient, hearing impairment and white matter strokes appeared to respectively related to impaired blood flow to the cochlea and white matter caused by platelet dysfunction triggered by physiologic stresses.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain and Development - Volume 28, Issue 1, January 2006, Pages 55–59
نویسندگان
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