کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3054409 | 1580052 | 2009 | 6 صفحه PDF | دانلود رایگان |
BackgroundSix term newborns presented with apnoea and temporal lobe haemorrhage.AimIn this observational study, we described involvement of the limbic system in apnoeic term newborns with temporal lobe injury.MethodsSix term newborns presented to the neonatal care unit with apnoea within the first 2 days of life. Ultrasound (US) and MRI of the brain were obtained in the first week of life.ResultsApnoea was related to temporal lobe haemorrhage in all. During apnoeic periods four had focal epileptic activity on EEG. All lesions were detected first with US. On MRI, haemorrhages were located in the parenchyma, the subdural and/or subarachnoid space. Three haemorrhages were surrounded by infarction in the temporal lobe. In three infants hippocampus and mesial temporal cortex were affected. In two basal temporal cortex only was involved. Vascular anomalies were excluded by MRA, serial MRI or serial US with Doppler imaging.ConclusionTerm infants with seizure associated apnoea may present with haemorrhage and/or infarction to hippocampus, mesial and basal temporal cortex. This study supports the existence and possible disruption of descending influences from the temporal cortex and/or amygdala on brainstem breathing centres in the term newborn.
Journal: European Journal of Paediatric Neurology - Volume 13, Issue 4, July 2009, Pages 356–361