کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3059707 1187433 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Memantine hydrochloride in the treatment of dementia subtypes
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Memantine hydrochloride in the treatment of dementia subtypes
چکیده انگلیسی

Memantine hydrochloride is a first-line therapeutic drug approved by the US Food and Drug Administration for the management of moderate to severe Alzheimer’s disease (AD). We conducted a review of the literature to determine the changes to the central glutamatergic neurotransmitter system in dementia subtypes and the available clinical evidence regarding the use of memantine in the treatment of different dementia subtypes. We conclude from our review that memantine may be an effective therapeutic option in managing AD, frontotemporal dementia, dementia with Lewy bodies, Parkinson’s disease dementia and vascular dementia. When a diagnosis of the dementia subtype cannot be clearly identified or when there is no clear therapeutic option, memantine may be simple and safe.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Neuroscience - Volume 20, Issue 11, November 2013, Pages 1482–1485
نویسندگان
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