Aneurysmal subarachnoid hemorrhage in young adults: A gender comparison study

Aneurysmal subarachnoid hemorrhage is uncommon in young adults. The aim of this study was to compare clinical characteristics of ruptured aneurysms between males and females in the third or fourth decade of life. We retrospectively investigated 301 patients who underwent surgery for ruptured cerebral aneurysms over 6 years. Among them, 53 patients were aged between 20–39 years. Clinical characteristics and related variables were compared between genders. In general, there was a favorable outcome in either gender (84.9%). There was a higher incidence of multiplicity and intraoperative rupture in females, as well as a significant difference in aneurysm location between genders (p = 0.030, p = 0.014, and p = 0.027 respectively). Overall outcome was not different between the two groups. These results suggest that aneurysm formation may differ between genders.